Yongqing Li Selected Research

Valproic Acid (Depakote)

10/2021	Assessment of the Cytoprotective Effects of High-Dose Valproic Acid Compared to a Clinically Used Lower Dose.
1/2021	Modulation of Brain Transcriptome by Combined Histone Deacetylase Inhibition and Plasma Treatment Following Traumatic Brain Injury and Hemorrhagic Shock.
11/2020	Histone deacetylase 6 inhibition improves survival in a swine model of lethal hemorrhage, polytrauma, and bacteremia.
10/2020	Valproic acid decreases resuscitation requirements after hemorrhage in a prolonged damage-control resuscitation model.
11/2019	Dose optimization of valproic acid in a lethal model of traumatic brain injury, hemorrhage, and multiple trauma in swine.
1/2019	HDAC inhibitor valproic acid protects heart function through Foxm1 pathway after acute myocardial infarction.
1/2019	Valproic acid improves survival and decreases resuscitation requirements in a swine model of prolonged damage control resuscitation.
1/2019	Comparative analysis of isoform-specific and non-selective histone deacetylase inhibitors in attenuating the intestinal damage after hemorrhagic shock.
1/2019	Valproic Acid and Neural Apoptosis, Inflammation, and Degeneration 30 Days after Traumatic Brain Injury, Hemorrhagic Shock, and Polytrauma in a Swine Model.
1/2019	Isoform 6-selective histone deacetylase inhibition reduces lesion size and brain swelling following traumatic brain injury and hemorrhagic shock.

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Yongqing Li Research Topics

Disease

41	Hemorrhagic Shock 01/2021 - 04/2006
35	Hemorrhage 01/2022 - 04/2006
31	Shock 01/2022 - 03/2008
19	Wounds and Injuries (Trauma) 10/2021 - 04/2008
16	Sepsis (Septicemia) 01/2022 - 08/2014
16	Neoplasms (Cancer) 01/2022 - 03/2003
15	Traumatic Brain Injuries (Traumatic Brain Injury) 11/2022 - 12/2013
15	Hypoxia (Hypoxemia) 04/2022 - 04/2008
14	Inflammation (Inflammations) 11/2022 - 08/2010
14	Infections 01/2022 - 05/2010
13	Septic Shock (Toxic Shock Syndrome) 02/2021 - 11/2009
10	Multiple Trauma (Multiple Injuries) 01/2021 - 12/2013
6	Carcinoma (Carcinomatosis) 01/2022 - 05/2002
6	Acute Lung Injury 08/2018 - 02/2012
5	Breast Neoplasms (Breast Cancer) 01/2021 - 08/2003
5	Hypothermia 06/2015 - 08/2006
4	Melanoma (Melanoma, Malignant) 01/2021 - 08/2005
4	Marek Disease (Marek's Disease) 11/2019 - 05/2010
3	Ischemia 10/2020 - 02/2012
3	Myocardial Infarction 10/2020 - 12/2015
3	Endotoxemia 08/2020 - 08/2013
3	Influenza in Birds (Avian Flu) 11/2019 - 05/2010
3	Atrophy 11/2016 - 08/2014
3	Cardiovascular Diseases (Cardiovascular Disease) 07/2016 - 07/2002
2	Non-alcoholic Fatty Liver Disease 01/2022 - 04/2021
2	Carcinogenesis 01/2022 - 10/2004
2	Necrosis 01/2022 - 12/2014
2	Virus Diseases (Viral Diseases) 01/2021 - 08/2008
2	Pneumonia (Pneumonitis) 01/2021 - 07/2012
2	Brain Edema (Cerebral Edema) 01/2019 - 01/2017

Drug/Important Bio-Agent (IBA)

32	Histone Deacetylase InhibitorsIBA 01/2021 - 06/2007
28	Valproic Acid (Depakote)FDA LinkGeneric 10/2021 - 03/2008
25	Proteins (Proteins, Gene)FDA Link 11/2022 - 03/2003
16	Histones (Histone)IBA 05/2021 - 06/2007
15	Saline SolutionIBA 01/2021 - 02/2008
14	LipopolysaccharidesIBA 05/2021 - 08/2008
14	Histone Deacetylases (Histone Deacetylase)IBA 01/2021 - 06/2007
13	salicylhydroxamic acid (SHAM)IBA 02/2016 - 06/2007
12	Vorinostat FDA Link 04/2015 - 11/2009
10	CytokinesIBA 04/2022 - 08/2005
9	Protein-Arginine DeiminasesIBA 05/2021 - 08/2014
9	Biomarkers (Surrogate Marker)IBA 01/2021 - 03/2010
8	AntigensIBA 03/2012 - 05/2002
7	Histone Deacetylase 6IBA 11/2020 - 07/2015
7	SolutionsIBA 12/2017 - 08/2006
6	Ringer's LactateIBA 01/2022 - 04/2006
6	EnzymesIBA 05/2021 - 08/2010
6	Transcription Factors (Transcription Factor)IBA 01/2021 - 07/2002
6	Caspase 3 (Caspase-3)IBA 01/2019 - 07/2009
6	Lactic Acid (Lactate)FDA LinkGeneric 12/2013 - 08/2009
5	tubastatin AIBA 12/2018 - 07/2015
4	Protein Isoforms (Isoforms)IBA 11/2020 - 01/2018
4	TubulinIBA 10/2020 - 01/2016
4	VaccinesIBA 11/2019 - 12/2006
4	Hydroxyethyl Starch Derivatives (Pentastarch)FDA Link 01/2017 - 04/2006
4	Oncogene Proteins (Oncogene Protein)IBA 06/2016 - 08/2003
4	Pyruvic Acid (Pyruvate)IBA 12/2013 - 04/2006
4	beta CateninIBA 08/2009 - 05/2002
3	ChemokinesIBA 04/2022 - 04/2007
3	Mitogen-Activated Protein KinasesIBA 01/2022 - 07/2012
3	CalciumIBA 10/2021 - 01/2019
3	N- alpha- benzoyl- N5- (2- chloro- 1- iminoethyl)- L- ornithine amideIBA 05/2021 - 08/2014
3	Blood Proteins (Serum Proteins)IBA 04/2021 - 03/2010
3	Pharmaceutical PreparationsIBA 01/2021 - 02/2012
3	Phosphotransferases (Kinase)IBA 01/2019 - 09/2010
3	ACY1083IBA 01/2019 - 01/2018
3	EpitopesIBA 12/2017 - 05/2004
3	Glycoproteins (Glycoprotein)IBA 12/2017 - 05/2002
3	MicroRNAs (MicroRNA)IBA 06/2016 - 01/2015
3	Interleukin-6 (Interleukin 6)IBA 02/2016 - 01/2015
3	Peptides (Polypeptides)IBA 06/2010 - 05/2004
3	KetonesIBA 02/2008 - 04/2006
3	Mucin-1 (CA 15-3 Antigen)IBA 11/2003 - 05/2002
2	Long Noncoding RNAIBA 01/2022 - 01/2022
2	Adenosine Triphosphate (ATP)IBA 10/2021 - 10/2020
2	Fatty Acids (Saturated Fatty Acids)IBA 10/2021 - 12/2016
2	Basic Helix-Loop-Helix Transcription FactorsIBA 04/2021 - 05/2006
2	ImmunosorbentsIBA 04/2021 - 08/2010
2	Antiviral Agents (Antivirals)IBA 01/2021 - 01/2018
2	Monoclonal AntibodiesIBA 01/2021 - 01/2019
2	InflammasomesIBA 01/2021 - 01/2021
2	ElementsIBA 01/2021 - 10/2020
2	Messenger RNA (mRNA)IBA 01/2020 - 08/2012
2	Doxorubicin (Adriamycin)FDA LinkGeneric 08/2019 - 12/2015
2	CyclodextrinsIBA 01/2019 - 01/2018
2	MC1568IBA 01/2019 - 01/2018
2	YW3-56IBA 08/2018 - 02/2016
2	Sodium Chloride FDA LinkGeneric 12/2017 - 04/2015
2	AntibodiesIBA 12/2017 - 05/2010
2	CollagenIBA 09/2017 - 01/2017
2	SteroidsIBA 12/2016 - 11/2016

Therapy/Procedure

36	Resuscitation 01/2022 - 04/2006
10	Therapeutics 01/2022 - 08/2005
8	Ligation 10/2020 - 08/2013
7	Punctures 12/2018 - 08/2013
4	Cardiopulmonary Bypass (Heart-Lung Bypass) 05/2010 - 08/2006
3	Lasers (Laser) 09/2018 - 03/2010
2	Segmental Mastectomy (Lumpectomy) 07/2021 - 01/2021
2	Drug Therapy (Chemotherapy) 05/2021 - 12/2015
2	Catheters 01/2018 - 04/2008